The academic board of the centre is charge with organization and control of lectures and tutorials, symposia, workshops, conferences etc in the subject areas of Mathematics, Statistics, Computer Science, Theoretical Physics and Mathematical Science Education. The broad subject area of Mathematic i.e. Algebra, Geometry, General and Global  Analysis ,Topology, Approximation Theory, Computational and Applied Mathematics, Mathematical Modeling ,Operation research, Systems and Control Theory etc. shall be given due attention. Similar attention are devoted to the usual key subct area of the other programmes.

Its responsibilities also include the admission and discipline of participants who are admitted into the centre to receive one course of instruction or the other.

The membership of the academic board, as stated in part IV, section 10 of Decree No. 40 of 1989, comprises the director of the centre as its Chairman, the Deputy Director, the Librarian, four representatives drawn in rotation from among the Universities in Nigeria in the discipline of Mathematical Sciences, and  five other persons, for the time being holding such appointments on the staff of the centre, as the Director of the Centre may, with the approval of the Council, specify.

The Academic Board is also expected to formulate and continuously evaluate the academic programmes of the centre, and perform other functions as are traditional to such bodies as the Director who is the Chairman of the Academic Board meetings, the Deputy Director shall preside at such meetings. However, in the absence of both, the members present at any of such a meeting, shall appoint one of their members to preside.

In the process of conducting the day to day management of the centre, the Governing Council and Academic Board require the services of committees to deal with particular area of work. These Committees could be standing committees or ad hoc committees.